Best HealthTech Companies in Pennsylvania, United States
The 785 best HealthTech companies in Pennsylvania, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Accolade.
Our analysis of 305 HealthTech companies
$32.1b in tracked funding; 95% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best HealthTech companies in Pennsylvania
| # | Company | Disclosed funding | Last round | Employees | Founder | Stage | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Accolade Cloud-based platform for employee health benefits | $228M | 56 mo ago | 2,299 | — | Acquired | HubSpot CMS HubApple iCloud MailElasticsearch+25 | — | — |
| 2 | Abridge Inc 🦄 Provider of AI-based health record platform | $208M | 12 mo ago | 17 | Zachary Lipton Co-Founder & CTO | Series E | WebflowApple iCloud MailGoogle Workspace+31 | 3 patents AI-powered conversation analysis and automated action extraction for enterprise communication tools | 1 launch |
| 3 | Aprecia Pharmaceuticals Develops & manufactures orodispersible formulations of highly prescribed high-dose medications using… | $176M | 119 mo ago | 87 87 → 65 (-25%) | Owen Murray CEO | Acquired | WordPressApple iCloud MailMySQL+25 | — | — |
| 4 | HealthVerity Cloud based healthcare and consumer data platform | $142M | 59 mo ago | 254 | Andrew Goldberg Co-Founder & COO | Series D | WordPressApple iCloud MailGoogle Workspace+32 | 3 patents Integrating relational, transaction, and social network data for healthcare analytics | 1 partnership |
| 5 | iECURE Online genetic engineering tool for drug development | $115M | 42 mo ago | 7 | Joseph Truitt CEO | Series A | — | — | 1 internship |
| 6 | Proscia Provider of an AI and cloud-based digital pathology solution for cancer diagnosis | $79M | 15 mo ago | 85 85 → 132 (+55%) | Nathan Buchbinder Co-Founder & Chief Strategy Officer | Series C | WordPressApple iCloud MailGoogle Workspace+33 | 64 patents AI-driven image analysis and workflow automation for digital pathology diagnostics | — |
| 7 | ParetoHealth Provider of health benefits solutions for midsize employers through community-based risk pooling | $78M | 36 mo ago | 124 | Andrew Cavenagh CEO | Series C | WordPressMySQLPHP+29 | — | — |
| 8 | Transparent Health Marketplace Provider of online marketplace for connecting payors and providers | $57M | 37 mo ago | 47 47 → 36 (-23%) | Eric Hanson Founder | Series C | — | — | 1 partnership |
| 9 | PeopleOne Health Provider of primary care services funded by employers for employees | $57M | 19 mo ago | 93 | Jordan Taradash Co-Founder & CEO | Series B | WordPress Site EditorWordPressApple iCloud Mail+26 | — | — |
| 10 | Novasenta Developer of a drug discovery platform for cancer therapies | $55M | 29 mo ago | 20 | Dario Vignali Co-Founder | Series A | — | 4 patents Therapeutic antibodies targeting CD161 for immunomodulation and disease treatment | — |
| 11 | NeuroFlow Provider of a platform for population health management | $52M | 33 mo ago | 26 | Christopher Molaro CEO | Series C | WordPressApple iCloud MailGoogle Workspace+29 | — | — |
| 12 | Sevaro Provider of telemedicine and consulting services for the healthcare sector | $50M | 12 mo ago | 32 | — | Series B | WordPressApple iCloud MailMicrosoft 365+34 | — | 1 job opening |
| 13 | Innovu Provider of cloud-based health benefits plans management solutions | $49M | 6 mo ago | 92 92 → 98 (+7%) | Brian Dinello Co-Founder & COO | Series A | WebflowZohoOptinMonster+13 | — | — |
| 14 | Genomind Developer of genetic tests for personalised medicines to enhance mental health treatment | $48M | 16 mo ago | 65 | Bill Brown CEO | Series C | WordPressMySQLPHP+28 | 32 patents Pharmacogenomic testing and reporting tools for mental health and drug response | — |
| 15 | Free Market Health Digital medication cost analysis and management tool for payers and pharmacies | $34M | 31 mo ago | 46 | Joe Cardosi Founder & CEO | Series B | — | — | 2 partnerships |
| 16 | Apollo Neuroscience Developer of wearable technology for stress reduction, sleep improvement, and performance enhancement | $31M | 26 mo ago | 12 | Kathryn Fantauzzi Co-Founder & CEO | Series A | Cart FunctionalityShopifySentry+46 | 20 patents Wearable haptic actuators for transcutaneous neuromodulation and sensory stimulation | — |
| 17 | MD Ally Provider of telemedicine platform for patients and professionals | $28M | 24 mo ago | 20 | Shanel Fields Founder & CEO | Series A | WordPress Block EditorWordPressApple iCloud Mail+26 | — | — |
| 18 | RIMSYS Provider of medical device regulatory management software for healthcare organizations | $26M | 26 mo ago | 31 31 → 31 (+0%) | James Gianoutsos Founder & President | Series A | WebflowApple iCloud MailMicrosoft 365+25 | — | 1 launch |
| 19 | Vitable Health Provider of healthcare solutions including primary care, mental health, and more | $25M | 22 mo ago | 38 | Joseph Kitonga Founder & CEO | Series A | WebflowGSAPAmazon Web Services+22 | — | — |
| 20 | LifeLens Developer of wireless ECG monitor for personal health monitoring use 37Talent top 28%Funding top 32%Product top 35%Moat top 38% All 9 signals ▾Talenttop 28% Fundingtop 32% Producttop 35% Moattop 38% Techbottom 48% Innovationbottom 47% Marketbottom 34% Patentsbottom 32% Globalbottom 31% Talent: 4 named leaders on record · 4 C-suite/founder profiles curated Funding: Raised $24.6M across 5 rounds · 5 rounds over 7 yrs (0.7/yr) rank vs industry peers · Fliar Intelligence Index 37/100 | $25M | 7 mo ago | 45 | David Robins Co-Founder | Series B | Wix eCommerceWixSentry+11 | 5 patents Patents concentrated in health & consumer products | — |
| 21 | FinPay Automated payment engagement and management platform for patients | $23M | 17 mo ago | 50 | Christopher Wolfington Founder/Board Member/Chief Revenue & Strategy Officer | Series D | HubSpot CMS HubAmazon Web Servicescore-js+15 | — | — |
| 22 | Ritten Provider of clinical practice management and medical record management tool | $17M | 6 mo ago | 26 | Gabriel Szczepanek Co-Founder | Series B | Webflow EcommerceWebflowSentry+26 | — | 1 job opening · 1 partnership |
| 23 | CoPilot Online platform providing personalized one-to-one fitness and nutrition coaching | $16M | 32 mo ago | 54 | Gabriel Madonna Co-Founder | Series A | — | 3 patents Patents concentrated in computing, sensing & instrumentation | — |
| 24 | Trainwell Online platform offering expert-led fitness training programs | $16M | 32 mo ago | — | Gabriel Madonna Co-Founder & CTO | Series A | WebflowReactKlaviyo Forms+19 | — | — |
| 25 | EtherMed AI AI-based tool provider EMr | $15M | 2 mo ago | 12 | Daniel Friedman Co-Founder & CEO | Series A | — | — | 2 launchs · 1 partnership |
| 26 | Ramp Health Provider of clinical, wellbeing, and safety solutions for employers | $13M | 26 mo ago | 539 | — | Acquired | WordPressMySQLPHP+28 | — | — |
| 27 | Intraprise Health Patient engagement and care coordination solution for healthcare providers | $12M | 26 mo ago | 54 | Cfche George Pappas Chief Executive Officer | Acquired | — | — | — |
| 28 | Progenra Developing innovative therapeutics targeting protein degradation for challenging diseases | $12M | 13 mo ago | 13 | Tauseef Butt President and CEO | Series A | — | 38 patents USP7-targeted small‑molecule inhibitors for cancer therapy and immune modulation | — |
| 29 | Epistemix Online population management software for healthcare providers | $12M | 26 mo ago | 20 20 → 23 (+15%) | — | Series A | — | — | — |
| 30 | Impilo Provider of integrated logistics and data solutions for digital health and remote patient monitoring | $12M | 19 mo ago | 10 | Josh Stein Founder | Series A | Apple iCloud MailGoogle WorkspaceReact+22 | — | 2 launchs |
| 31 | AblePay Health Medical bill payment solution for healthcare providers | $11M | 26 mo ago | 40 | John Fistner Founder & CEO | Series B | WordPressApple iCloud MailMicrosoft 365+26 | — | 5 partnerships |
| 32 | Arya Cloud-based platform for compensation planning | $7M | 25 mo ago | 4 | Kunal Sarda Founder | Series A | SentryApple iCloud MailGoogle Workspace+13 | — | — |
| 33 | Twenty30 Health Platform offering obesity management solutions for individuals | $7M | 24 mo ago | — | Rajesh Aggarwal Founder & CEO | Series A | WordPressMySQLPHP+21 | — | — |
| 34 | Pharma Solutions Provider of compliance automation software for pharmaceutical industries 45Moat top 28%Patents top 33%Growth top 35%Innovation top 41% All 9 signals ▾Moattop 28% Patentstop 33% Growthtop 35% Innovationtop 41% Fundingtop 42% Talentbottom 49% Techbottom 46% Globalbottom 35% Marketbottom 34% Moat: Editorial + unicorn rating 4/10 · IP moat: 248 patents Patents: 248 patents matched (strict assignee match) · 33 filings since 2022 vs 99 in 2017-21 rank vs industry peers · Fliar Intelligence Index 45/100 | $7M | 2 mo ago | 43 | Sumeet Singh Founder & CEO | Series A | WordPressMySQLPHP+29 | 248 patents Oral zirconium silicate potassium binders for hyperkalemia treatment | — |
| 35 | Bainbridge Health Provider of a clinical intelligence data analytics platform to monitor patient safety and reduce medication… | $6M | 13 mo ago | 11 11 → 27 (+145%) | — | Series A | HubSpot CMS HubAzureUptrends+16 | — | 1 job opening |
| 36 | ThirdLaw Molecular Drug discovery platform developing peptide molecules | $6M | 9 mo ago | — | Christian Schafmeister Founder | Series A | — | — | — |
| 37 | Living Beyond Breast Cancer Provider of information and support for navigating a breast cancer diagnosis | $5M | 13 mo ago | 66 | Jean Sachs Ceo | Funding Raised | WordPressSite Search 360MySQL+36 | — | 1 job opening |
| 38 | BioPhy Provider of AI operating system that accelerates the identification and development of the most promising… | $4M | 15 mo ago | — | Daniel Sciubba Co-Founder | Series A | — | — | — |
| 39 | SurgeonCheck SaaS-based analytics platform that provides insights into surgeon quality | $4M | 17 mo ago | 8 | — | Seed | WordPress Site EditorWordPressMySQL+24 | — | 1 launch · 1 partnership |
| 40 | PHRASE Health Decision support tool for healthcare providers at the point of care | $3M | 10 mo ago | 18 | — | Series A | HubSpot CMS HubApple iCloud MailGoogle Workspace+22 | — | — |
| 41 | Waypoint Orthopedics Provider of decision support solutions for orthopedic surgery 10Talent top 38%Funding bottom 46%Global bottom 37%Market bottom 17% All 4 signals ▾Talenttop 38% Fundingbottom 46% Globalbottom 37% Marketbottom 17% Talent: 2 named leaders on record · 2 C-suite/founder profiles curated Funding: Raised $3.0M across 8 rounds · 8 rounds over 5 yrs (1.6/yr) rank vs industry peers · Fliar Intelligence Index 10/100 | $3M | 3 mo ago | 2 | Stephen Banco Founder | Seed | — | — | — |
| 42 | Estenda Custom software, data, and AI solutions transforming healthcare and MedTech | $3M | 13 mo ago | 32 | — | Funding Raised | WordPressMySQLPHP+27 | — | — |
| 43 | Resilient Lifescience Provider of drug overdose detection device | $2M | 12 mo ago | 5 | Charlie Proctor Co-Founder | Seed | — | — | — |
| 44 | Noctem Provider of telemedicine platform to optimise sleep management solutions 11Talent bottom 49%Funding bottom 45%Tech bottom 40%Product bottom 40% All 6 signals ▾Talentbottom 49% Fundingbottom 45% Techbottom 40% Productbottom 40% Globalbottom 29% Marketbottom 24% Talent: 1 named leader on record · 1 C-suite/founder profile curated Funding: Raised $1.5M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 11/100 | $1M | 3 mo ago | 17 | Anne Germain Founder & CEO | Seed | Cart FunctionalitySquarespace CommerceSquarespace+16 | — | — |
| 45 | Temple Health Online platform for booking doctors appointments | $823K | 14 mo ago | 9,036 | — | Funding Raised | DrupalPHPVarnish+16 | — | — |
| 46 | Flagship Management Provider of fitness equipment to rehabilitation centers | $785K | 11 mo ago | 31 | Dan Kervick Co-Founder & CEO | Early Stage | — | — | — |
| 47 | NextEvo Naturals Provider of cannabis-derived nutritional and wellness products | $725K | 17 mo ago | 7 | John Mcdonagh President & CEO | Seed | Cart FunctionalityShopifyBootstrap+30 | — | — |
| 48 | Moberg Analytics Cloud-based neuromonitoring platform for the detection of brain diseases | $600K | 7 mo ago | — | Dick Moberg Founder & CEO | Seed | WordPressMySQLPHP+21 | — | 1 launch |
| 49 | Noma AI-based clinical decision support and patient monitoring solutions | $350K | 13 mo ago | 6 | — | Seed | PHPBootstrapApache HTTP Server+11 | — | — |
| 50 | HeartIO Provider of AI-based platform for the diagnosis of heart abnormalities | $200K | 3 mo ago | 3 | Nick Flanigan Co-Founder | Seed | — | — | — |
Top 12 HealthTech companies in Pennsylvania
#1
Series A · Pittsburgh, Pennsylvania · founded 2014 · 92 employees$49.1Mraised▾
Provider of cloud-based health benefits plans management solutions. The platform provides analytics solutions to help employers optimize their healthcare and benefits programs' quality, cost, and efficacy. It integrates benefits data from multiple sources, performs validity checks, and applies descriptive and predictive analytics on the curated data to provide employers with actionable insights.
- Dec 2025Series A$1.3M
- Feb 2024Series A$3M
- Dec 2022Series A$6M
- Apr 2020Series A$4.6M
#2
Series E · Pittsburgh, Pennsylvania · founded 2018 · 17 employees$207.5Mraised▾
Provider of AI-based health record platform. It offers a platform offering solutions for individuals to record health details. The users can communicate with the doctors on the care needs and symptoms. The recorded conversation can be presented to the doctor during the appointment. The app highlights the important points during the conversation. The previous record can be maintained in the app for future reference.
- Jun 2025Series E$315.9M
- Feb 2025Series D$250M
- Feb 2024Series C$150M
- Oct 2023Series B$30M
#3
Series A · Philadelphia, Pennsylvania · founded 2018 · 12 employees$15Mraised▾
EtherMed is a medical assistant with AI for medical charting. The platform provides pre-filled EMR after every patient. AI assistants can be customized and data is encrypted at every point in transit and in rest.
- Apr 2026Series A$8.5M
- 2025Series A—
- Seed$6.5M
#4
Series B · Warminster, Pennsylvania · founded 2014 · 45 employees$24.6Mraised▾
Developer of wireless ECG monitor for personal health monitoring use. The monitor is indicated for use on patients who may be asymptomatic. It can also be used for patients who may suffer from transient symptoms. These symptoms include palpitations, shortness of breath, dizziness, and fatigue. The monitor is intended for use by patients eighteen years or older. The system is not yet cleared for other indications.
- Nov 2025Series B$15.1M
- Jun 2024Series B$18.4M
- Sep 2021Series A$78.2K
- Jul 2020Series A$3.2M
#5
Series A · Merion, Pennsylvania · founded 2015 · 43 employees$6.7Mraised▾
Provider of compliance automation software for pharmaceutical industries. The company offers compliance solutions to support the drug and device supply chain which include initial assessments, obtaining new licenses, ongoing renewals, and state compliance filings.
- Mar 2026Series A$7.9M
- Jun 2023Series A$6.7M
- Nov 2021Seed$500K
#6
Series B · Philadelphia, Pennsylvania · founded 2020 · 26 employees$17.5Mraised▾
Provider of clinical practice management and medical record management tool. The company offers tools for clinicians to help with their daily tasks and practice management. The product has features for real-time decision making, optimization of daily tasks, medical records management, workflow management, and others.
- Dec 2025Series B$35M
- May 2024Series B$11.5M
- Jan 2022Series A$6M
#7
Seed · Philadelphia, Pennsylvania · founded 2020 · 2 employees$3Mraised▾
Provider of decision support solutions for orthopedic surgery. The company offers the product Waypoint GPS. The features allow doctors to see the color of the bone as they traverse through the pedicle in preparation for screw placement. They also provide a smart pedicle probe that utilizes proprietary color-sensing technology.
- Mar 2026Seed$300K
- Sep 2025Seed$50K
- Jun 2025Seed$30K
- Dec 2024Seed$35K
#8
Series C · Philadelphia, Pennsylvania · founded 2014 · 85 employees$79.2Mraised▾
Proscia’s is a cloud-based software platform that clinic management, analysis, access, and collaboration for slide images in digital pathology. The features of the Proscia platform that allow users to improve whole slide image workflows include secure storage, annotation, and collaboration on digital biopsies. The company has developed a digital pathology platform called Concentriq that uses AI technology for computational pathology applications. The company has developed a tool that assists helathacre providers to diagnose cancer cells using image analysis technology.
- Mar 2025Series C$50M
- Dec 2023Series C$9M
- Jun 2022Series C$37M
- Nov 2020Series B$23M
#9
Series B · Philadelphia, Pennsylvania · founded 2013 · 32 employees$50Mraised▾
Provider of telemedicine and consulting services for the healthcare sector. The telemedicine company provides custom teleneurology programs that improve patient outcomes. It offers OneCall, which is an intelligent communication system that improves emergent neurological care.
- Jun 2025Series B$39M
- Feb 2023Series B$11M
#10
Series C · King Of Prussia, Pennsylvania · founded 2009 · 65 employees$47.8Mraised▾
Developer of genetic tests for personalised medicines to enhance mental health treatment. It offers Genomind's PGx test that examines genes related to mental health treatment, providing insights into how a patient may metabolize or respond to different medication. It also offer Mental Health Map a DNA test that assesses genetic predispositions across core mental health capabilities, including mood, focus, and stress responses.
- Feb 2025Grant (prize money)$399.6K
- Sep 2023Grant (prize money)$399.6K
- Apr 2021Series C$6.4M
- Jul 2018Series C$20.6M
#11
Series A · Malvern, Pennsylvania · founded 2002 · 13 employees$12Mraised▾
Developing innovative therapeutics targeting protein degradation for challenging diseases. The company is focused on advancing a new class of medicine through Molecular Glues and targeted protein degradation. Their platform leverages the ubiquitin system to develop therapies for challenging diseases, including neurodegenerative diseases like Parkinson’s and Alzheimer’s, cardiovascular disorders, metabolic dysfunction, and aging-related conditions. The company is engaged in drug discovery, delivering a pipeline of first-in-class therapeutics. They are exploring partnerships to further their reach and impact in the pharmaceutical industry. Their research focuses on areas like mitochondria, the Ubiquitin Proteasome System (UPS), and phospho-ubiquitin to restore mitochondrial functions and address diseases. The company is committed to innovation and redefining treatment paradigms through targeted protein degradation.
- May 2025Grant (prize money)$302.4K
- 2024Grant (prize money)$269.6K
- 2022Grant (prize money)$551.5K
- 2021Grant (prize money)$266K
#12
Seed · Pittsburgh, Pennsylvania · founded 2018 · 17 employees$1.5Mraised▾
Noctem provides a telemedicine platform to optimize sleep management solutions. The company offers a digital platform which helps the practitioners and sleeps clinics to give real-time personalized sleep recommendation solutions to patients for better health outcomes.
- Feb 2026Seed$1.5M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of HealthTech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Digital Health in Pennsylvania is moving
A read on the academic research around Digital Health in Pennsylvania — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 143 papers.
Penn and Penn State lead Pennsylvania's digital health research, focusing on EHR systems and mental health interventions, with a cautiously optimistic but concern-dominated stance reflecting policy and implementation challenges.
- University of Pennsylvania85
- Pennsylvania State University26
- California University of Pennsylvania21
- University of Pennsylvania Health System12
- Hospital of the University of Pennsylvania5
- Informatics1→8
- Health informatics4→7
- Health informatics2→16
- Health care2→12
- Health administration1→9
- Public health2→9