Best Blockchain Technology Companies in San Francisco, United States
The 651 best Blockchain Technology companies in San Francisco, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Forte.
Our analysis of 81 Blockchain Technology companies
$9.2b in tracked funding; 100% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Blockchain Technology companies in San Francisco
| # | Company | Disclosed funding | Last round | Stage | Employees | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Tempo Developer of a layer 1 blockchain designed for payment solutions 48Funding top 18%Tech top 37%Talent top 38%Global bottom 46% All 7 signals ▾Fundingtop 18% Techtop 37% Talenttop 38% Globalbottom 46% Innovationbottom 42% Marketbottom 37% Patentsbottom 37% Funding: Raised $500M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Tech: 27 technologies across 5/8 capability areas · Cloud: Cloudflare, Vercel rank vs industry peers · Fliar Intelligence Index 48/100 | $500M | 8 mo ago | Series A | — | Matt Huang CEO | ContentfulApple iCloud MailGoogle Workspace+14 | 8 patents HVAC ventilation control systems and collaborative team scheduling software | 2 launchs |
| 2 | Anchorage Digital 🦄 Digital asset platform providing trading, custody, staking, settlement, and crypto financial infrastructure 74Funding top 16%News top 16%Growth top 26%Moat top 26% All 11 signals ▾Fundingtop 16% Newstop 16% Growthtop 26% Moattop 26% Talenttop 28% Producttop 33% Markettop 34% Techtop 48% Globaltop 48% Innovationbottom 45% Partnersbottom 43% Funding: Raised $487M across 5 rounds · 5 rounds over 8 yrs (0.6/yr) News: 9 BI events in 12 mo (of 13 tracked, 5 types) · 8 high-value events (IPO/M&A/funding/contracts) in 12 mo rank vs industry peers · Fliar Intelligence Index 74/100 | $487M | 4 mo ago | Series E | 349 | Nathan McCauley Co-Founder and CEO | WebflowSalesforceGSAP+28 | — | 1 launch · 2 partnerships |
| 3 | Phantom 🦄 Provider of a self-custodial cryptocurrency wallet with multi-chain support 87Customers top 13%Tech top 19%Funding top 20%Market top 27% All 12 signals ▾Customerstop 13% Techtop 19% Fundingtop 20% Markettop 27% Moattop 27% Talenttop 28% AItop 30% Patentstop 38% Innovationtop 40% Producttop 40% Growthtop 50% Globalbottom 48% Customers: Play-Store rating 4.56★ across 148,178 ratings (1 apps) Tech: 51 technologies across 7/8 capability areas · Cloud: Amazon Ses, Amazon Web Services rank vs industry peers · Fliar Intelligence Index 87/100 | $277M | 17 mo ago | Series C | — | Chris Kalani Co-Founder & CPO | Node.jsReactNext.js App Router+16 | 73 patents Patents concentrated in computing, sensing & instrumentation | — |
| 4 | Aleo 🦄 Blockchain-based network for developers 69Funding top 22%Moat top 26%Growth top 35%Talent top 38% All 8 signals ▾Fundingtop 22% Moattop 26% Growthtop 35% Talenttop 38% Markettop 41% Techtop 43% Globalbottom 38% Newsbottom 32% Funding: Raised $228M across 3 rounds · 3 rounds over 5 yrs (0.6/yr) Moat: Editorial + unicorn rating 9/10 · Unicorn rank vs industry peers · Fliar Intelligence Index 69/100 | $228M | 15 mo ago | Series B | 55 | Michael Beller Co-Founder | ContentfulReactGatsby+12 | — | 1 partnership |
| 5 | TRM Labs 🦄 Provider of blockchain intelligence for detecting crypto-facilitated crime and compliance 64Funding top 18%News top 19%Moat top 26%Growth top 29% All 9 signals ▾Fundingtop 18% Newstop 19% Moattop 26% Growthtop 29% Techtop 31% Talenttop 43% Producttop 45% Marketbottom 40% Globalbottom 39% Funding: Raised $150M across 6 rounds · 6 rounds over 7 yrs (0.9/yr) News: 6 BI events in 12 mo (of 35 tracked, 6 types) · 4 high-value events (IPO/M&A/funding/contracts) in 12 mo rank vs industry peers · Fliar Intelligence Index 64/100 | $150M | 4 mo ago | Series C | 11 | Rahul Raina Co-Founder | WebflowMemberStackApple iCloud Mail+28 | — | 1 launch |
| 6 | Superstate Provider of tokenization services for financial assets and investment products 53Funding top 23%Talent top 28%Tech top 44%Global top 45% All 5 signals ▾Fundingtop 23% Talenttop 28% Techtop 44% Globaltop 45% Marketbottom 37% Funding: Raised $101M across 3 rounds · 3 rounds over 3 yrs (1.0/yr) Talent: 3 named leaders on record · 3 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 53/100 | $101M | 2 mo ago | Series B | — | Robert Leshner Co-Founder & CEO | SentryNode.jsRadix UI+17 | — | — |
| 7 | Portal to Bitcoin Decentralized bitcoin exchange and interoperability protocol 62Talent top 28%Funding top 31%Tech top 34%Moat top 40% All 7 signals ▾Talenttop 28% Fundingtop 31% Techtop 34% Moattop 40% Growthtop 45% Globaltop 45% Marketbottom 46% Talent: 3 named leaders on record · 3 C-suite/founder profiles curated Funding: Raised $92.5M across 3 rounds · 3 rounds over 5 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 62/100 | $92M | 9 mo ago | Series A | — | Manoj Duggirala Co-founder | DatoCMSNode.jsThree.js+15 | — | — |
| 8 | Bitwise Provider of crypto index funds, ETFs, and managed accounts 67Funding top 20%Tech top 28%Talent top 38%Moat top 39% All 6 signals ▾Fundingtop 20% Techtop 28% Talenttop 38% Moattop 39% Markettop 46% Globalbottom 43% Funding: Raised $91.2M across 4 rounds · 4 rounds over 9 yrs (0.4/yr) Tech: 38 technologies across 5/8 capability areas · Cloud: Cloudflare, Vercel rank vs industry peers · Fliar Intelligence Index 67/100 | $91M | 15 mo ago | Public | 74 | Hunter Horsley Co-Founder & CEO | DatoCMSTurbopackNode.js+28 | — | 1 partnership |
| 9 | Sentient Non-profit organization advancing open-source AGI research | $85M | 23 mo ago | Seed | — | Himanshu Tyagi Co-Founder & Co-CEO | NotionSuper BuilderNode.js+14 | 21 patents Patents concentrated in health & consumer products | 1 launch |
| 10 | Uphold Digital assets trading platform offering trading services for cryptocurrencies, stablecoins, and precious… 55Tech top 20%Customers top 23%Funding top 27%Innovation top 30% All 12 signals ▾Techtop 20% Customerstop 23% Fundingtop 27% Innovationtop 30% Moattop 31% Patentstop 35% Producttop 49% Talentbottom 49% Newsbottom 46% Globalbottom 44% Growthbottom 38% Marketbottom 33% Tech: 56 technologies across 6/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3 Customers: Play-Store rating 4.49★ across 73,095 ratings (1 apps) · Review volume +1% in 6 mo rank vs industry peers · Fliar Intelligence Index 55/100 | $73M | 2 mo ago | Series B | 14 | JP Thieriot CEO | SkolengoApple iCloud MailGoogle Workspace+26 | 8 patents Blockchain-enabled financial transaction processing, analytics, and tokenized payment platforms | 1 launch |
| 11 | Bridge Provider of stablecoin infrastructure and APIs for developers and businesses | $58M | 21 mo ago | Acquired | 13 | Sean Yu Co-Founder | Node.jsKaTeXRadix UI+24 | — | 3 launchs · 3 partnerships |
| 12 | Huma Finance Protocol offering decentralized risk and lending solutions backed by income and receivables | $46M | 21 mo ago | Series A | 9 | Ji Peng Co-Founder | Apple iCloud MailGoogle WorkspaceYouTube+17 | — | — |
| 13 | Conduit Provider of optimistic rollup for scaling | $44M | 23 mo ago | Series A | 5 | Andrew Huang Founder | Apple iCloud MailGoogle WorkspaceNode.js+14 | 6 patents Point‑of‑care saliva viral diagnostics and AI‑driven health documentation/linking tools | 1 launch · 1 partnership |
| 14 | Fabric Developer of hardware-accelerated cryptography solutions for real-time, high-performance systems | $39M | 21 mo ago | Series A | 23 | Tina Ju Co-Founder | WebflowApple iCloud MailGoogle Workspace+10 | — | — |
| 15 | Mesh Online platform for cryptocurrency solutions 62News top 20%Funding top 25%Growth top 32%Tech top 32% All 10 signals ▾Newstop 20% Fundingtop 25% Growthtop 32% Techtop 32% Talenttop 38% Moattop 39% Producttop 49% Marketbottom 42% Globalbottom 38% Partnersbottom 35% News: 7 BI events in 12 mo (of 29 tracked, 7 types) · +250% YoY Funding: Raised $36.5M across 5 rounds · 5 rounds over 5 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 62/100 | $36M | 10 mo ago | Series B | 44 | Bam Azizi Co-Founder & CEO | WebflowApple iCloud MailGoogle Workspace+17 | — | 3 partnerships |
| 16 | 0G Labs AI-based programmable layer for dApps development | $35M | 19 mo ago | Seed | — | Ming Wu Co-Founder & CTO | Turbopackstyled-componentsSentry+18 | — | 2 launchs · 1 award |
| 17 | Sei Online platform offering blockchain infrastructure solutions | $35M | 23 mo ago | Series B | 41 | — | GhostNode.jsKaTeX+15 | 24 patents Mobile content delivery, device activation, near‑field power, and secure element transaction management | — |
| 18 | Centrifuge Provider of the decentralized platform to connect the financial supply chain 55Talent top 15%Funding top 32%Tech top 34%Growth top 35% All 7 signals ▾Talenttop 15% Fundingtop 32% Techtop 34% Growthtop 35% Moattop 39% Globalbottom 47% Marketbottom 25% Talent: Analyst team rating 5/5 Funding: Raised $27.1M across 4 rounds · 4 rounds over 8 yrs (0.5/yr) rank vs industry peers · Fliar Intelligence Index 55/100 | $27M | 1 mo ago | Series A | 10 | — | WebflowMicrosoft AdvertisingCloudflare Turnstile+16 | — | 2 launchs · 2 partnerships |
| 19 | Aidatify Decentralized finance (DeFi) strategy aggregator | $26M | 22 mo ago | Series A | — | Jason Runyon Founder | — | — | — |
| 20 | Kresus Web3 app intended to let users create mint, manage, and store digital assets 40Funding top 26%Customers top 32%Tech top 42%Growth top 45% All 9 signals ▾Fundingtop 26% Customerstop 32% Techtop 42% Growthtop 45% Moattop 48% Talentbottom 49% Productbottom 48% Globalbottom 36% Marketbottom 25% Funding: Raised $25.0M across 2 rounds · 2 rounds over 3 yrs (0.7/yr) Customers: Play-Store rating 4.60★ across 283 ratings (1 apps) rank vs industry peers · Fliar Intelligence Index 40/100 | $25M | 3 mo ago | Series A | 6 | Trevor Traina Founder & Chairman | WordPress Block EditorWordPressMySQL+32 | — | 1 partnership |
| 21 | Caldera Developer of infrastructure for building and scaling custom blockchain networks | $25M | 22 mo ago | Series A | 7 | Matthew Katz Co-Founder & CEO | Node.jsNextAuth.jsRadix UI+17 | 6 patents Patents concentrated in chemistry & materials | — |
| 22 | Irreducible Blockchain-based zero knowledge proofs platform | $24M | 16 mo ago | Series A | — | Jim Posen Co-Founder & CTO | Framer SitesKaTeXVimeo+12 | — | — |
| 23 | Bitwave Accounting solutions for crypocurrencies | $22M | 20 mo ago | Series A | 5 | Amy Kalnoki COO | WebflowApple iCloud MailGoogle Workspace+20 | — | 1 partnership |
| 24 | Kontigo Provider of stablecoin super app for emerging markets with digital wallet 69Growth top 11%Funding top 27%Customers top 29%Tech top 39% All 8 signals ▾Growthtop 11% Fundingtop 27% Customerstop 29% Techtop 39% Talentbottom 49% Globalbottom 48% Marketbottom 40% Productbottom 40% Growth: App-install growth +500% YoY · Fresh capital in last 24 mo Funding: Raised $20.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 69/100 | $20M | 5 mo ago | Seed | — | Gino Guatavita Co-Founder | TurbopackNode.jsTailwind CSS+17 | — | — |
| 25 | Provenance Public & distributed stakeholder blockchain for the financial services industry | $20M | 19 mo ago | Series B | 18 | Alana Aldag Ackerson Co-Founder | Apple iCloud MailGoogle WorkspaceECharts+16 | — | 1 launch |
| 26 | CoinRoutes Algorithm trading platform for cryptocurrency 42Talent top 28%Funding top 31%Moat top 37%Tech bottom 49% All 8 signals ▾Talenttop 28% Fundingtop 31% Moattop 37% Techbottom 49% Innovationbottom 46% Patentsbottom 40% Globalbottom 39% Marketbottom 38% Talent: Analyst team rating 5/5 · 2 named leaders on record Funding: Raised $19.0M across 2 rounds · 2 rounds over 7 yrs (0.3/yr) rank vs industry peers · Fliar Intelligence Index 42/100 | $19M | 3 mo ago | Series B | 33 | Michael Holstein Co-Founder & CCO | TurbopackApple iCloud MailGoogle Workspace+14 | 13 patents Crypto trading infrastructure: smart order routing, pricing calculation, and consolidated market data. | 1 partnership · 1 award |
| 27 | Kite Developer of a blockchain infrastructure for autonomous agents and AI systems 78Funding top 28%Tech top 28%AI top 30%Market top 35% All 10 signals ▾Fundingtop 28% Techtop 28% AItop 30% Markettop 35% Innovationtop 36% Talenttop 38% Patentstop 39% Moattop 41% Globaltop 50% Growthbottom 48% Funding: Raised $18.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Tech: 39 technologies across 4/8 capability areas · Cloud: Amazon Alb, Amazon S3 rank vs industry peers · Fliar Intelligence Index 78/100 | $18M | 7 mo ago | Series A | — | Chi Zhang Co-Founder & CEO | Node.jsThree.jsRadix UI+15 | 11 patents Patents concentrated in transport & manufacturing processes | 2 launchs · 3 partnerships |
| 28 | Legend Provider of DeFi crypto wallet platform | $15M | 20 mo ago | Seed | — | Jayson Hobby Co-Founder | Tailwind CSSReactReact Router+5 | 5 patents Image-based depth estimation and enhancement for 2D-to-3D conversion and video workflows | — |
| 29 | Block Street Operator of a blockchain-based financial infrastructure company trading tokenized equities 50Funding top 30%Talent top 38%Tech top 50%Global bottom 48% All 5 signals ▾Fundingtop 30% Talenttop 38% Techtop 50% Globalbottom 48% Marketbottom 47% Funding: Raised $11.5M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 50/100 | $12M | 8 mo ago | Series B | — | Hedy W. Co-Founder & CEO | Tailwind CSSReactReact Router+8 | — | — |
| 30 | Alpen Labs Bitcoin platform with zero knowledge technology | $11M | 17 mo ago | Series B | 5 | Pramod Kandel Co-Founder & CTO | WebflowGSAPAmazon Web Services+19 | — | 1 launch · 1 partnership |
| 31 | YOProtocol Protocol optimizing yield across multiple DeFi protocols and blockchains 45Funding top 35%Growth top 35%Tech top 44%Talent bottom 49% All 6 signals ▾Fundingtop 35% Growthtop 35% Techtop 44% Talentbottom 49% Globalbottom 48% Marketbottom 31% Funding: Raised $10.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 45/100 | $10M | 6 mo ago | Series A | — | Driss Benamour Co-Founder & CEO | SanityNode.jsTailwind CSS+14 | — | 1 launch |
| 32 | AIUSD Provider of AI technology to power the next generation of income and transactions 50Talent top 38%AI top 45%Funding top 48%Global bottom 25% All 4 signals ▾Talenttop 38% AItop 45% Fundingtop 48% Globalbottom 25% Talent: 2 named leaders on record · 2 C-suite/founder profiles curated AI: Product described with: ai-driven rank vs industry peers · Fliar Intelligence Index 50/100 | $10M | 7 mo ago | Seed | — | Yao Meng Co-Founder | — | — | — |
| 33 | Pieverse Developer of blockchain interoperability infrastructure to unify decentralized network connectivity 42Funding top 33%Talent top 38%Global top 45%Tech top 50% All 5 signals ▾Fundingtop 33% Talenttop 38% Globaltop 45% Techtop 50% Marketbottom 37% Funding: Raised $10.0M across 2 rounds · 2 rounds over 1 yrs (2.0/yr) Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 42/100 | $10M | 7 mo ago | Seed | — | Colin Ho Co-Founder & CEO | TurbopackNode.jsThree.js+14 | — | — |
| 34 | Doppler Developer of tools for creating and launching tokenized assets and markets 62AI top 15%Growth top 28%Funding top 35%Innovation top 42% All 9 signals ▾AItop 15% Growthtop 28% Fundingtop 35% Innovationtop 42% Techtop 44% Patentstop 46% Talentbottom 49% Globalbottom 42% Marketbottom 31% AI: Holds AI/ML patents (G06N-family CPC) Growth: Web rank 50,000,000 → 10,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 62/100 | $9M | 4 mo ago | Seed | — | Austin Adams Founder | Turbopackstyled-componentsNode.js+13 | 55 patents AI-driven real-time audio processing and noise suppression for hearing assistance devices | — |
| 35 | Self Labs Provider of digital identity verification using zero-knowledge cryptography for Web2/Web3 42Talent top 28%Growth top 35%Tech top 41%Funding top 49% All 8 signals ▾Talenttop 28% Growthtop 35% Techtop 41% Fundingtop 49% Productbottom 40% Customersbottom 35% Globalbottom 33% Marketbottom 30% Talent: 3 named leaders on record · 3 C-suite/founder profiles curated Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 42/100 | $9M | 7 mo ago | Seed | — | Marek Olszewski Co-Founder | GitBookApple iCloud MailNode.js+11 | — | 4 launchs |
| 36 | Masa Developer of a layer-1 blockchain for AI-powered trading strategies | $9M | 17 mo ago | Series A | — | Brendan Playford Co-Founder | Node.jsReactNext.js+18 | — | — |
| 37 | Meld Online platform offering stack as a service for developers to manage third-party financial integrations 45Tech top 33%Growth top 35%Funding top 38%Talent top 38% All 7 signals ▾Techtop 33% Growthtop 35% Fundingtop 38% Talenttop 38% Moattop 48% Globalbottom 37% Marketbottom 24% Tech: 33 technologies across 4/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3 Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 45/100 | $8M | 5 mo ago | Seed | 8 | Hank Pham Co-Founder & CTO | Node.jsRechartsRadix UI+16 | — | — |
| 38 | Rift Developer of a platform for managing and trading digital assets 37Funding top 48%Tech top 50%Talent bottom 49%Innovation bottom 47% All 6 signals ▾Fundingtop 48% Techtop 50% Talentbottom 49% Innovationbottom 47% Globalbottom 46% Patentsbottom 34% Funding: Raised $8.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Tech: 13 technologies across 4/8 capability areas · Cloud: Cloudflare, Vercel rank vs industry peers · Fliar Intelligence Index 37/100 | $8M | 7 mo ago | Series A | — | Samee Siddiqui CEO | Node.jsChakra UIReact+10 | 14 patents Scalable virtualized network functions and load‑balancing for telecom infrastructure | — |
| 39 | Blueprint Finance Provider of financial services and wealth management solutions | $8M | 11 mo ago | Series A | — | Nic Huntley Co-Founder & CEO | — | — | 1 partnership |
| 40 | Courtyard NFT-based trading platform for physical collectibles 82Tech top 20%Growth top 22%Customers top 30%Funding top 35% All 9 signals ▾Techtop 20% Growthtop 22% Customerstop 30% Fundingtop 35% Markettop 37% Talenttop 38% Productbottom 48% Moatbottom 38% Globalbottom 36% Tech: 45 technologies across 6/8 capability areas · Cloud: Cloudflare, Google Cloud Growth: App-install growth +500% YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 82/100 | $7M | 10 mo ago | Series A | 93 | Paulin A. Co-Founder & CTO | Cart FunctionalityTurbopackstyled-components+29 | — | 1 launch |
| 41 | Octane Security Vulnerability management solution | $7M | 14 mo ago | Seed | — | Giovanni Vignone Founder & CEO | WebflowGSAPMicrosoft Clarity+19 | — | — |
| 42 | Multipli Platform providing cross-chain secure yield farming solutions 69Talent top 28%Tech top 32%Global top 36%Funding top 39% All 5 signals ▾Talenttop 28% Techtop 32% Globaltop 36% Fundingtop 39% Growthtop 45% Talent: 3 named leaders on record · 3 C-suite/founder profiles curated Tech: 31 technologies across 5/8 capability areas · Cloud: Cloudflare, Netlify rank vs industry peers · Fliar Intelligence Index 69/100 | $5M | 9 mo ago | Series A | — | Ritumbhara Bhatnagar Co-Founder | SentryZohoReact Router+13 | — | — |
| 43 | Evernorth Provider of digital asset treasury services focused on tomorrow’s markets 27Funding top 40%Talent top 45%Tech top 48%Global bottom 48% All 5 signals ▾Fundingtop 40% Talenttop 45% Techtop 48% Globalbottom 48% Marketbottom 25% Funding: Raised $4.5M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Talent: 2 named leaders on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 27/100 | $4M | 7 mo ago | Seed | — | Asheesh Birla CEO | Craft CMSApple iCloud MailGoogle Workspace+15 | — | — |
| 44 | Fun API for cross-chain decentralized wallets on the Odsy blockchain 50Growth top 35%Moat top 39%Funding top 40%Tech top 40% All 7 signals ▾Growthtop 35% Moattop 39% Fundingtop 40% Techtop 40% Talentbottom 49% Marketbottom 41% Globalbottom 36% Growth: Fresh capital in last 24 mo Moat: Editorial + unicorn rating 7/10 · 9 curated direct competitors tracked rank vs industry peers · Fliar Intelligence Index 50/100 | $4M | 1 mo ago | Series A | 22 | Alex Fine Co-Founder & CEO | Webflow EcommerceCart FunctionalityWebflow+14 | — | — |
| 45 | Wallchain Platform utilizing AI-driven algorithm to measure and reward users for generating content engagement 60Tech top 22%Growth top 28%AI top 45%Funding bottom 45% All 6 signals ▾Techtop 22% Growthtop 28% AItop 45% Fundingbottom 45% Globalbottom 38% Marketbottom 33% Tech: 39 technologies across 6/8 capability areas · Cloud: Cloudflare, Google Cloud Growth: Web rank 5,000,000 → 1,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 60/100 | $4M | 7 mo ago | Seed | 7 | — | Turbopackstyled-componentsEmotion+14 | — | — |
| 46 | Unicity Developer of infrastructure for autonomous agent marketplaces and machine-speed commerce 13Talent bottom 49%Funding bottom 48%Tech bottom 40%Global bottom 35% All 7 signals ▾Talentbottom 49% Fundingbottom 48% Techbottom 40% Globalbottom 35% Innovationbottom 34% Patentsbottom 26% Marketbottom 25% Talent: 1 named leader on record · 1 C-suite/founder profile curated Funding: Raised $3.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 13/100 | $3M | 4 mo ago | Seed | — | Mike Gault Founder & CEO | WebflowSwiperjQuery+9 | 3 patents Nutraceutical fiber matrices for metabolic regulation and controlled-release biologic delivery | — |
| 47 | Uniblock Web3 infrastructure to facilitate the development of decentralized applications 53Tech top 31%Growth top 35%Talent top 38%Innovation top 46% All 9 signals ▾Techtop 31% Growthtop 35% Talenttop 38% Innovationtop 46% Fundingtop 46% Moattop 47% Patentsbottom 49% Globalbottom 39% Marketbottom 33% Tech: 32 technologies across 5/8 capability areas · Cloud: Cloudflare, Vercel Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 53/100 | $2M | 2 mo ago | Seed | 14 | James Liu VP Engineering & Co-Founder | Node.jsMUIReact+12 | 3 patents Adaptive modulation metric selection for OFDM subcarrier transmission | 1 job opening · 3 launchs |
| 48 | Interstate Provider of decentralized and interoperable Ethereum L1 blockchain platform 24Global top 45%Talent bottom 49%Funding bottom 46%Tech bottom 36% All 4 signals ▾Globaltop 45% Talentbottom 49% Fundingbottom 46% Techbottom 36% Global: Investors from 3 countries beyond United States Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 24/100 | $2M | 3 mo ago | Seed | — | Irfan Shaik Founder | WebflowjsDelivrGoogle Hosted Libraries+7 | — | — |
| 49 | Shred Pay Provider of a gateway to Web3 for higher crypto yields | $1M | 9 mo ago | Seed | — | Melissa Muehlfeld Co-Founder & President | — | — | — |
| 50 | Sponge Provider of financial infrastructure enabling agent accounts and direct business sales | $500K | 5 mo ago | Seed | — | Rishab Luthra Co-Founder | — | — | 2 launchs |
Top 12 Blockchain Technology companies in San Francisco
#1
Series E · San Francisco, California · founded 2017 · 349 employees$487Mraised▾
Digital asset platform providing trading, custody, staking, settlement, and crypto financial infrastructure. It is designed for financial institutions and professional investors, it provides secure custody through a federally chartered banking entity and enables seamless access to liquidity, risk-managed execution, and compliant digital asset operations. It supports end-to-end workflows across cash and crypto assets, combining advanced market infrastructure with regulatory-grade security, governance, and institutional controls for managing and scaling digital asset strategies.
- Feb 2026Series E$100M
- Jun 2022Series D—
- Dec 2021Series D$350M
- Feb 2021Series C$80M
#2
Series B · San Francisco, California · founded 2023$100.6Mraised▾
Provider of tokenization services for financial assets and investment products. The company connects assets with crypto capital markets through onchain public listings. It offers tokenized funds and tokenized shares of public companies. The company's platform facilitates compliant onchain equity listings and direct issuance programs.
- Apr 2026Series B—
- Jan 2026Series B$82.5M
- Sep 2023Series A$14.1M
- Jun 2023Seed$4M
#3
TRM Labs 🦄Series C · San Francisco, California · founded 2018 · 11 employees$149.9Mraised▾
Provider of blockchain intelligence for detecting crypto-facilitated crime and compliance. The platform offers tools for investigations, compliance, and supervision of digital assets. It facilitates transaction monitoring, wallet screening, and entity due diligence. The company provides resources such as training, reports, webinars, and guides.
- Feb 2026Series C$70M
- Nov 2022Series B$70M
- Feb 2022Series B—
- Dec 2021Series B$60M
#4
Series B · San Francisco, California · founded 2013 · 14 employees$73.4Mraised▾
Digital assets trading platform offering a wide range of cryptocurrencies, precious metals, and national currencies. They allow users to trade anything to anything and provides two-factor authentication and an API suite for enterprise clients. The platform has a mobile app for on-the-go trading.
- Apr 2026Series B—
- Jan 2018Angel$57.5M
- Jan 2016Series B$1.9M
- Dec 2014Series B$9.9M
#5
Series A · San Francisco, California · founded 2017$500Mraised▾
Developer of a layer 1 blockchain designed for payment solutions. The blockchain supports stablecoins, enabling high-throughput, low-cost global transactions for various business applications. It offers embedded payment features, including memo fields and batch transfers. The blockchain facilitates remittances, global payouts, embedded finance, microtransactions, agentic commerce, and tokenized deposits. Technical features include fee flexibility, dedicated payments lane, stablecoin interoperability, and compliance measures.
- Oct 2025Series A$500M
#6
Series A · San Francisco, California · founded 2017 · 10 employees$27.1Mraised▾
Provider of the decentralized platform to connect the financial supply chain. It allows businesses to transact on a network while maintaining ownership of their data, including validated company details, business relationships, and transactions. It also enables businesses to exchange financial documents such as invoices, purchase orders, and company data.
- May 2026Series A—
- Apr 2024Series A$15M
- Nov 2023Series A—
- Nov 2022Series A$4M
#7
Series A · San Francisco, California · founded 2022 · 6 employees$25Mraised▾
Web3 app intended to let users create mint, manage, and store digital assets. The application curates interesting web3 finds, teaches users how to mint NFT, offers ongoing education about the evolving landscape, and connects users with exciting communities.
- Feb 2026Series A$13M
- Mar 2023Series A$25M
#8
Series B · San Francisco, California · founded 2017 · 33 employees$19Mraised▾
Algorithm trading platform for cryptocurrency It offers CoinRoutes RealPrice which displays investable prices, filtered CBBO which is a research tool for crypto assets, and a cost calculator. It also provides a client-deployed smart order router that facilitates multi-exchange trading.
- Feb 2026Series B—
- Mar 2022Series B$16M
- Oct 2019Seed$3M
#9
Series A · San Francisco, California · founded 2018$92.5Mraised▾
Decentralized bitcoin exchange and interoperability protocol. It offers a custody-less interoperability protocol for Bitcoin, allowing for atomic swaps between native Bitcoin assets. Its provides a secure and self-custodial gateway to the vast universe of Web3 decentralized applications.
- Aug 2025Series A$50M
- Jan 2024Seed$34M
- Sep 2021Seed$8.5M
#10
Aleo 🦄Series B · San Francisco, California · founded 2019 · 55 employees$228Mraised▾
Blockchain-based network for developers. Its features of the platform include a zero-knowledge IDE, package manager, etc. The platform features enable developers to build custom cross-platform mobile applications.
- Mar 2025Series B$480K
- Feb 2022Series B$200M
- Apr 2021Series A$28M
#11
Phantom 🦄Series C · San Francisco, California · founded 2021$277Mraised▾
Provider of a self-custodial cryptocurrency wallet with multi-chain support. The wallet allows users to manage and showcase NFTs, swap tokens, stake tokens, and earn rewards. It offers tools for managing NFTs, including pinning, hiding, burning, and listing. The wallet incorporates scam detection and supports ledger integration for enhanced security. It does not require personal information such as name, email, or phone number.
- Jan 2025Series C$150M
- Jan 2022Series B$109M
- Jul 2021Series A$9M
- May 2021Series A$9M
#12
Seed · San Francisco, California · founded 2023$20Mraised▾
Provider of stablecoin super app for emerging markets with digital wallet. It offers a platform for saving in USDC, investing in BTC, and spending with local stablecoins. The platform provides a self-custody wallet for sending, receiving, and saving USDC. It also offers a card for international USDC credit and debit transactions.
- Dec 2025Seed$20M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Blockchain Technology coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Blockchain is moving in the United States
A read on the academic research around Blockchain — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 5,117 United States-affiliated papers.
- Community Partners293
- Northeastern University125
- University of the Cumberlands81
- Old Dominion University75
- The University of Texas at San Antonio66
- Computer security17→846
- Scalability3→216
- Smart contract2→160
- Database transaction2→160
- Distributed computing2→159
- Computer security7→633
- Supply chain1→196
- Transparency (behavior)2→158
- Database transaction4→132
- Cryptocurrency5→118
- Computer security18→380
- Cryptocurrency12→133
- Distributed ledger4→69
- Data science1→59
- Key (lock)3→52
Where blockchain is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing blockchain patents in the United States
United States blockchain patent filing is accelerating — 11,538 filings from 2,143 assignees (2016–2025), led by IBM, Mastercard International, BANK Of America; annual filings 32→1298.
- IBM1155
- Mastercard International594
- BANK Of America350
- State FARM Mutual Automobile Ins228
- Capital One Services216
- Paypal200
- Jpmorgan Chase BANK NA183
- VISA INT Service ASS174